Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.

Abdollahi-Roodsaz, Shahla; Joosten, Leo A B; Koenders, Marije I; Devesa, Isabel; Roelofs, Mieke F; Radstake, Timothy R D J; Heuvelmans-Jacobs, Marleen; Akira, Shizuo; Nicklin, Martin J H; Ribeiro-Dias, Fátima; van den Berg, Wim B

Abdollahi-Roodsaz, Shahla; Joosten, Leo A B; Koenders, Marije I; Devesa, Isabel; Roelofs, Mieke F; Radstake, Timothy R D J; Heuvelmans-Jacobs, Marleen; Akira, Shizuo; Nicklin, Martin J H; Ribeiro-Dias, Fátima; van den Berg, Wim B.

Affiliation

Abdollahi-Roodsaz S; Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. s.abdollahi-roodsaz@reuma.umcn.nl

J Clin Invest ; 118(1): 205-16, 2008 Jan.

Article in En | MEDLINE | ID: mdl-18060042

Subject(s)

Arthritis, Rheumatoid/immunology; Germ-Free Life/immunology; Lymphocyte Activation/immunology; T-Lymphocytes, Regulatory/immunology; Toll-Like Receptor 2/immunology; Toll-Like Receptor 4/immunology; Animals; Arthritis, Rheumatoid/genetics; Arthritis, Rheumatoid/microbiology; Disease Models, Animal; Germ-Free Life/genetics; Humans; Interleukin 1 Receptor Antagonist Protein/genetics; Interleukin 1 Receptor Antagonist Protein/immunology; Interleukin-17/immunology; Lymphocyte Activation/genetics; Mice; Mice, Inbred BALB C; Mice, Knockout; Toll-Like Receptor 2/genetics; Toll-Like Receptor 4/genetics; Toll-Like Receptor 9/genetics; Toll-Like Receptor 9/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Lymphocyte Activation / T-Lymphocytes, Regulatory / Toll-Like Receptor 2 / Toll-Like Receptor 4 / Germ-Free Life Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2008 Type: Article Affiliation country: Netherlands

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