Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice.

Glauben, R; Batra, A; Stroh, T; Erben, U; Fedke, I; Lehr, H A; Leoni, F; Mascagni, P; Dinarello, C A; Zeitz, M; Siegmund, B

Glauben, R; Batra, A; Stroh, T; Erben, U; Fedke, I; Lehr, H A; Leoni, F; Mascagni, P; Dinarello, C A; Zeitz, M; Siegmund, B.

Affiliation

Glauben R; Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Department of Medicine I, Hindenburgdamm 30, D-12200 Berlin, Germany.

Gut ; 57(5): 613-22, 2008 May.

Article in En | MEDLINE | ID: mdl-18194985

Subject(s)

Anti-Inflammatory Agents/therapeutic use; Anticarcinogenic Agents/therapeutic use; Colitis/prevention & control; Colonic Neoplasms/prevention & control; Histone Deacetylase Inhibitors; Hydroxamic Acids/therapeutic use; Animals; Apoptosis/drug effects; Colitis/enzymology; Colonic Neoplasms/enzymology; Colonic Neoplasms/etiology; Cytokines/biosynthesis; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B/metabolism; Vorinostat

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anticarcinogenic Agents / Colitis / Colonic Neoplasms / Histone Deacetylase Inhibitors / Hydroxamic Acids / Anti-Inflammatory Agents Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Gut Year: 2008 Type: Article Affiliation country: Germany

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