Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation.

de Cueto, M; Rodríguez, J M; Soriano, M J; López-Cerero, L; Venero, J; Pascual, A

de Cueto, M; Rodríguez, J M; Soriano, M J; López-Cerero, L; Venero, J; Pascual, A.

Affiliation

de Cueto M; Departamento de Microbiología, Hospital Virgen Macarena, Avda. Dr. Fedriani s/n, 41009 Seville, Spain. m@marinadecueto.e.telefonica.net

J Clin Microbiol ; 46(4): 1558-60, 2008 Apr.

Article in En | MEDLINE | ID: mdl-18287316

Subject(s)

Anti-Bacterial Agents/therapeutic use; Bacteremia/drug therapy; DNA Topoisomerase IV/genetics; Levofloxacin; Mutation; Ofloxacin/therapeutic use; Pneumonia, Pneumococcal/drug therapy; Streptococcus pneumoniae/drug effects; Aged; Bacteremia/microbiology; DNA Gyrase/genetics; Drug Resistance, Bacterial/genetics; Fatal Outcome; Humans; Male; Pneumonia, Pneumococcal/microbiology; Streptococcus pneumoniae/enzymology; Streptococcus pneumoniae/genetics; Treatment Failure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Pneumococcal / Streptococcus pneumoniae / Ofloxacin / Bacteremia / DNA Topoisomerase IV / Levofloxacin / Anti-Bacterial Agents / Mutation Limits: Aged / Humans / Male Language: En Journal: J Clin Microbiol Year: 2008 Type: Article Affiliation country: Spain

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