Rational design, selection and specificity of artificial transcription factors (ATFs): the influence of chromatin in target gene regulation.

Blancafort, Pilar; Beltran, Adriana S

Blancafort, Pilar; Beltran, Adriana S.

Affiliation

Blancafort P; Department of Pharmacology and the Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7365, USA. pilar_blancafort@med.unc.edu

Comb Chem High Throughput Screen ; 11(2): 146-58, 2008 Feb.

Article in En | MEDLINE | ID: mdl-18336208

Subject(s)

Chromatin/genetics; Gene Expression Regulation/genetics; Gene Targeting; Transcription Factors/genetics; Animals; DNA/genetics; Drug Design; Humans; Nucleic Acid Conformation; Phenotype; Protein Engineering; Zinc Fingers/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Chromatin / Gene Expression Regulation / Gene Targeting Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Comb Chem High Throughput Screen Journal subject: BIOLOGIA MOLECULAR / QUIMICA Year: 2008 Type: Article Affiliation country: United States

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