Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca-ATPase.

Xu, Xiao-Le; Chen, Xiang-Jian; Ji, Hui; Li, Ping; Bian, Yun-Yun; Yang, Di; Xu, Jin-Dan; Bian, Zhi-Ping; Zhang, Ji-Nan

Xu, Xiao-Le; Chen, Xiang-Jian; Ji, Hui; Li, Ping; Bian, Yun-Yun; Yang, Di; Xu, Jin-Dan; Bian, Zhi-Ping; Zhang, Ji-Nan.

Affiliation

Xu XL; Department of Pharmacology, China Pharmaceutical University, Nanjing, PR China.

Pharmacology ; 81(4): 325-32, 2008.

Article in En | MEDLINE | ID: mdl-18349554

Subject(s)

Calcium/metabolism; Saponins/pharmacology; Sarcoplasmic Reticulum Calcium-Transporting ATPases/drug effects; Triterpenes/pharmacology; Animals; Animals, Newborn; Astragalus propinquus/chemistry; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Fluorescent Dyes/metabolism; Fura-2/analogs & derivatives; Fura-2/metabolism; Gene Expression Regulation/drug effects; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/metabolism; Oxygen/metabolism; RNA, Messenger/drug effects; RNA, Messenger/metabolism; Rats; Saponins/administration & dosage; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism; Triterpenes/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saponins / Triterpenes / Calcium / Sarcoplasmic Reticulum Calcium-Transporting ATPases Limits: Animals Language: En Journal: Pharmacology Year: 2008 Type: Article

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