A tumor-selective biotherapy with prolonged impact on established metastases based on cytokine gene-engineered MSCs.

Chen, Xiancheng; Lin, Xiaojuan; Zhao, Jianlei; Shi, Wei; Zhang, Heng; Wang, Yongsheng; Kan, Bing; Du, Licheng; Wang, Baiding; Wei, Yuquan; Liu, Yi; Zhao, Xia

Chen, Xiancheng; Lin, Xiaojuan; Zhao, Jianlei; Shi, Wei; Zhang, Heng; Wang, Yongsheng; Kan, Bing; Du, Licheng; Wang, Baiding; Wei, Yuquan; Liu, Yi; Zhao, Xia.

Affiliation

Chen X; Department of Gynecology and Obstetrics, West China Medical School, Second West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.

Mol Ther ; 16(4): 749-56, 2008 Apr.

Article in En | MEDLINE | ID: mdl-18362930

Subject(s)

Breast Neoplasms/therapy; Carcinoma, Hepatocellular/therapy; Interleukin-12/genetics; Liver Neoplasms/therapy; Melanoma, Experimental/therapy; Mesenchymal Stem Cells/metabolism; Adenoviridae/genetics; Animals; Breast Neoplasms/immunology; Breast Neoplasms/pathology; Carcinoma, Hepatocellular/immunology; Carcinoma, Hepatocellular/secondary; Cell Line, Tumor; Cell Movement; Feasibility Studies; Female; Genetic Therapy; Immunotherapy; Interleukin-12/biosynthesis; Liver Neoplasms/immunology; Liver Neoplasms/pathology; Lymph Nodes/pathology; Lymphatic Vessels/pathology; Melanoma, Experimental/immunology; Melanoma, Experimental/secondary; Mesenchymal Stem Cell Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Vascular Endothelial Growth Factor D/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Melanoma, Experimental / Breast Neoplasms / Carcinoma, Hepatocellular / Interleukin-12 / Mesenchymal Stem Cells / Liver Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2008 Type: Article

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