Source of high pathogenicity of an avian influenza virus H5N1: why H5 is better cleaved by furin.

Decha, Panita; Rungrotmongkol, Thanyada; Intharathep, Pathumwadee; Malaisree, Maturos; Aruksakunwong, Ornjira; Laohpongspaisan, Chittima; Parasuk, Vudhichai; Sompornpisut, Pornthep; Pianwanit, Somsak; Kokpol, Sirirat; Hannongbua, Supot

Decha, Panita; Rungrotmongkol, Thanyada; Intharathep, Pathumwadee; Malaisree, Maturos; Aruksakunwong, Ornjira; Laohpongspaisan, Chittima; Parasuk, Vudhichai; Sompornpisut, Pornthep; Pianwanit, Somsak; Kokpol, Sirirat; Hannongbua, Supot.

Affiliation

Decha P; Department of Chemistry, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok 10330, Thailand.

Biophys J ; 95(1): 128-34, 2008 Jul.

Article in En | MEDLINE | ID: mdl-18375507

Subject(s)

Furin/chemistry; Furin/ultrastructure; Hemagglutinin Glycoproteins, Influenza Virus/chemistry; Hemagglutinin Glycoproteins, Influenza Virus/ultrastructure; Influenza A Virus, H5N1 Subtype/chemistry; Influenza A Virus, H5N1 Subtype/pathogenicity; Models, Chemical; Computer Simulation; Influenza A Virus, H5N1 Subtype/ultrastructure; Models, Molecular; Peptide Hydrolases/chemistry; Peptide Hydrolases/ultrastructure

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemagglutinin Glycoproteins, Influenza Virus / Furin / Influenza A Virus, H5N1 Subtype / Models, Chemical Language: En Journal: Biophys J Year: 2008 Type: Article Affiliation country: Thailand

Fulltext

XML

PubMed Links

Search on Google