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Severe autoimmune hemolytic anemia in a liver transplanted child.
Schäppi, Michela G; Ozsahin, Hulya; Peyrard, Thierry; Gumy-Pause, Fabienne; Posfay-Barbe, Klara M; Chardot, Christophe; Belli, Dominique C; Siegenthaler, Michèle A.
Affiliation
  • Schäppi MG; Division of Paediatric Gastroenterology and Transplantation, Children's Hospital of Geneva, Geneva, Switzerland. michela.schaeppi@hcuge.ch
Pediatr Transplant ; 12(7): 809-12, 2008 Nov.
Article in En | MEDLINE | ID: mdl-18433411
AIHA can complicate solid organ and bone marrow transplantation early after transplant. We describe the first case report of a 16-month-old boy with mixed type warm-acting IgM and warm IgG autoantibodies AIHA, occurring eight months after liver transplantation. This case describes the complexity of this very rare form of AIHA. It also illustrates the efficacy of rituximab in this indication, as well as the transfusion support with extremely rare blood, along with the importance of international collaboration to provide it. In this report, the etiologies of HA occurring in post-transplant pediatric patients are reviewed and the different treatment strategies are discussed.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Liver Transplantation / Anemia, Hemolytic, Autoimmune / Liver Diseases Limits: Child / Humans / Infant / Male Language: En Journal: Pediatr Transplant Journal subject: PEDIATRIA / TRANSPLANTE Year: 2008 Type: Article Affiliation country: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Liver Transplantation / Anemia, Hemolytic, Autoimmune / Liver Diseases Limits: Child / Humans / Infant / Male Language: En Journal: Pediatr Transplant Journal subject: PEDIATRIA / TRANSPLANTE Year: 2008 Type: Article Affiliation country: Switzerland