Therapeutic potential of angiogenin modified mesenchymal stem cells: angiogenin improves mesenchymal stem cells survival under hypoxia and enhances vasculogenesis in myocardial infarction.

Liu, Xiao-Hong; Bai, Chen-Guang; Xu, Zhi-Yun; Huang, Sheng-Dong; Yuan, Yang; Gong, De-Jun; Zhang, Jian-Rong

Liu, Xiao-Hong; Bai, Chen-Guang; Xu, Zhi-Yun; Huang, Sheng-Dong; Yuan, Yang; Gong, De-Jun; Zhang, Jian-Rong.

Affiliation

Liu XH; Institute of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, PR China.

Microvasc Res ; 76(1): 23-30, 2008 May.

Article in En | MEDLINE | ID: mdl-18462761

Subject(s)

Mesenchymal Stem Cell Transplantation/methods; Mesenchymal Stem Cells/metabolism; Myocardial Infarction/therapy; Neovascularization, Physiologic; Ribonuclease, Pancreatic/physiology; Actins/analysis; Adenoviridae/genetics; Angiogenic Proteins/genetics; Angiogenic Proteins/metabolism; Angiogenic Proteins/physiology; Animals; Antigens, CD/analysis; Capillaries/anatomy & histology; Cell Hypoxia; Cell Survival/physiology; Collagen/metabolism; Gene Expression; Genetic Vectors/genetics; HLA-DR Antigens/analysis; Male; Mesenchymal Stem Cells/cytology; Myocardial Infarction/metabolism; Myocardial Infarction/physiopathology; Myocardium/metabolism; Myocardium/pathology; Rats; Rats, Inbred Lew; Ribonuclease, Pancreatic/genetics; Ribonuclease, Pancreatic/metabolism; Transfection; Ventricular Function, Left/physiology; Ventricular Remodeling/physiology; Vimentin/analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonuclease, Pancreatic / Neovascularization, Physiologic / Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells / Myocardial Infarction Type of study: Prognostic_studies Limits: Animals Language: En Journal: Microvasc Res Year: 2008 Type: Article

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