Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

Taylor, Kimberly E; Remmers, Elaine F; Lee, Annette T; Ortmann, Ward A; Plenge, Robert M; Tian, Chao; Chung, Sharon A; Nititham, Joanne; Hom, Geoffrey; Kao, Amy H; Demirci, F Yesim; Kamboh, M Ilyas; Petri, Michelle; Manzi, Susan; Kastner, Daniel L; Seldin, Michael F; Gregersen, Peter K; Behrens, Timothy W; Criswell, Lindsey A

Taylor, Kimberly E; Remmers, Elaine F; Lee, Annette T; Ortmann, Ward A; Plenge, Robert M; Tian, Chao; Chung, Sharon A; Nititham, Joanne; Hom, Geoffrey; Kao, Amy H; Demirci, F Yesim; Kamboh, M Ilyas; Petri, Michelle; Manzi, Susan; Kastner, Daniel L; Seldin, Michael F; Gregersen, Peter K; Behrens, Timothy W; Criswell, Lindsey A.

Affiliation

Taylor KE; Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, California, USA.

PLoS Genet ; 4(5): e1000084, 2008 May 30.

Article in En | MEDLINE | ID: mdl-18516230

Subject(s)

Genetic Predisposition to Disease; Lupus Erythematosus, Systemic/complications; Lupus Erythematosus, Systemic/genetics; STAT4 Transcription Factor/genetics; Adult; Antibodies, Antinuclear/blood; Case-Control Studies; Chromosomes, Human, Pair 2/genetics; DNA/blood; DNA/immunology; Female; Genotype; Humans; Linkage Disequilibrium; Lupus Erythematosus, Systemic/immunology; Lupus Nephritis/genetics; Male; Phenotype; Polymorphism, Single Nucleotide; Risk Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / STAT4 Transcription Factor / Lupus Erythematosus, Systemic Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2008 Type: Article Affiliation country: United States

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