Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function.

Rota, Marcello; Padin-Iruegas, M Elena; Misao, Yu; De Angelis, Antonella; Maestroni, Silvia; Ferreira-Martins, João; Fiumana, Emanuela; Rastaldo, Raffaella; Arcarese, Michael L; Mitchell, Thomas S; Boni, Alessandro; Bolli, Roberto; Urbanek, Konrad; Hosoda, Toru; Anversa, Piero; Leri, Annarosa; Kajstura, Jan

Rota, Marcello; Padin-Iruegas, M Elena; Misao, Yu; De Angelis, Antonella; Maestroni, Silvia; Ferreira-Martins, João; Fiumana, Emanuela; Rastaldo, Raffaella; Arcarese, Michael L; Mitchell, Thomas S; Boni, Alessandro; Bolli, Roberto; Urbanek, Konrad; Hosoda, Toru; Anversa, Piero; Leri, Annarosa; Kajstura, Jan.

Affiliation

Rota M; Department of Anesthesia and Division of Cardiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. mrota@zeus.bwh.harvard.edu

Circ Res ; 103(1): 107-16, 2008 Jul 03.

Article in En | MEDLINE | ID: mdl-18556576

Subject(s)

Cicatrix/therapy; Heart Failure/therapy; Myocardial Infarction/therapy; Myocardium; Stem Cell Transplantation; Stem Cells; Animals; Cell Movement/drug effects; Chronic Disease; Cicatrix/etiology; Cicatrix/metabolism; Cicatrix/pathology; Collagen/metabolism; Collagenases/biosynthesis; Diploidy; Heart Failure/metabolism; Heart Failure/pathology; Hemodynamics; Hepatocyte Growth Factor/metabolism; Hepatocyte Growth Factor/pharmacology; Humans; Insulin-Like Growth Factor I/metabolism; Insulin-Like Growth Factor I/pharmacology; Myocardial Infarction/complications; Myocardial Infarction/metabolism; Myocardial Infarction/pathology; Myocardium/metabolism; Myocardium/pathology; Myocytes, Cardiac/metabolism; Myocytes, Cardiac/pathology; Rats; Regeneration/drug effects; Stem Cell Transplantation/methods; Stem Cells/metabolism; Stem Cells/pathology; Transplantation, Homologous; Ventricular Dysfunction/etiology; Ventricular Dysfunction/metabolism; Ventricular Dysfunction/pathology; Ventricular Dysfunction/therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Cicatrix / Stem Cell Transplantation / Heart Failure / Myocardial Infarction / Myocardium Type of study: Etiology_studies Language: En Journal: Circ Res Year: 2008 Type: Article Affiliation country: United States

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