Lactational exposure to hexavalent chromium delays puberty by impairing ovarian development, steroidogenesis and pituitary hormone synthesis in developing Wistar rats.

Banu, Sakhila K; Samuel, Jawahar B; Arosh, Joe A; Burghardt, Robert C; Aruldhas, Michael M

Banu, Sakhila K; Samuel, Jawahar B; Arosh, Joe A; Burghardt, Robert C; Aruldhas, Michael M.

Affiliation

Banu SK; Reproductive Endocrinology and Cell Signaling Laboratory, Texas A&M University, TAMU 4458, College Station, Texas 77843, USA. skbanu@cvm.tamu.edu

Toxicol Appl Pharmacol ; 232(2): 180-9, 2008 Oct 15.

Article in En | MEDLINE | ID: mdl-18602937

Subject(s)

Chromium/toxicity; Lactation; Ovary/drug effects; Ovary/growth & development; Pituitary Hormones/biosynthesis; Sexual Maturation/drug effects; Age Factors; Animals; Animals, Newborn; Ascorbic Acid/administration & dosage; Cell Line; Chromium/administration & dosage; Female; Gonadal Steroid Hormones/antagonists & inhibitors; Gonadal Steroid Hormones/biosynthesis; Gonadal Steroid Hormones/genetics; Lactation/blood; Ovary/metabolism; Pituitary Hormones/antagonists & inhibitors; Pituitary Hormones/genetics; Pregnancy; Rats; Rats, Wistar; Sexual Maturation/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovary / Pituitary Hormones / Sexual Maturation / Lactation / Chromium Limits: Animals / Pregnancy Language: En Journal: Toxicol Appl Pharmacol Year: 2008 Type: Article Affiliation country: United States

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