Alendronate lowers cholesterol synthesis in the central nervous system of rats - a preliminary study.

Cibickova, L; Hyspler, R; Cibicek, N; Cermakova, E; Palicka, V

Cibickova, L; Hyspler, R; Cibicek, N; Cermakova, E; Palicka, V.

Affiliation

Cibickova L; Second Department of Medicine, University Hospital, Hradec Králové, Czech Republic. cibickova@seznam.cz

Physiol Res ; 58(3): 455-458, 2009.

Article in En | MEDLINE | ID: mdl-18637708

Subject(s)

Alendronate/pharmacology; Brain/drug effects; Cholesterol/biosynthesis; Enzyme Inhibitors/pharmacology; Geranyltranstransferase/antagonists & inhibitors; Spinal Cord/drug effects; Animals; Basal Ganglia/drug effects; Basal Ganglia/metabolism; Brain/metabolism; Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; Cholesterol/blood; Geranyltranstransferase/metabolism; Hippocampus/drug effects; Hippocampus/metabolism; Kinetics; Male; Rats; Rats, Wistar; Spinal Cord/metabolism

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord / Brain / Cholesterol / Alendronate / Enzyme Inhibitors / Geranyltranstransferase Limits: Animals Language: En Journal: Physiol Res Journal subject: FISIOLOGIA Year: 2009 Type: Article Affiliation country: Czech Republic

Search on Google

XML

PubMed Links