Therapeutic strategies for inhibiting oncogenic BRAF signaling.

Halilovic, Ensar; Solit, David B

Halilovic, Ensar; Solit, David B.

Affiliation

Halilovic E; Program in Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

Curr Opin Pharmacol ; 8(4): 419-26, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18644254

Subject(s)

Antineoplastic Agents/pharmacology; Antineoplastic Agents/therapeutic use; Neoplasms/drug therapy; Neoplasms/genetics; Proto-Oncogene Proteins B-raf/antagonists & inhibitors; Proto-Oncogene Proteins B-raf/genetics; Signal Transduction/drug effects; Animals; Humans; MAP Kinase Kinase Kinases/antagonists & inhibitors; Mutation/drug effects; Mutation/physiology; raf Kinases/antagonists & inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Proto-Oncogene Proteins B-raf / Neoplasms / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Curr Opin Pharmacol Journal subject: FARMACOLOGIA Year: 2008 Type: Article Affiliation country: United States

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