[Influence of mifepristone on DNA repair genes and cisplatin sensitivity in human ovarian cancer drug-resistance cells].

Liu, Guo-Yan; Qu, Quan-Xin; Mi, Ruo-Ran; Qi, Jing

Liu, Guo-Yan; Qu, Quan-Xin; Mi, Ruo-Ran; Qi, Jing.

Affiliation

Liu GY; Department of Obstetrics and Gynecology, General Hospital, Tianjin Medical University, Tianjin 300052, China. liuguoyan211@126.com

Zhonghua Fu Chan Ke Za Zhi ; 43(2): 132-5, 2008 Feb.

Article in Zh | MEDLINE | ID: mdl-18683754

Subject(s)

Apoptosis/drug effects; Cisplatin/pharmacology; DNA Repair; Mifepristone/pharmacology; Ovarian Neoplasms/pathology; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/metabolism; Animals; Antineoplastic Agents/pharmacology; BRCA1 Protein/genetics; BRCA1 Protein/metabolism; Cell Cycle/drug effects; Cell Line, Tumor; Cisplatin/administration & dosage; DNA Damage; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Endonucleases/genetics; Endonucleases/metabolism; Female; Humans; Mice; Mice, Nude; Mifepristone/administration & dosage; MutL Protein Homolog 1; Neoplasm Transplantation; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Ovarian Neoplasms/genetics; Ovarian Neoplasms/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Mifepristone / Cisplatin / Apoptosis / DNA Repair Type of study: Diagnostic_studies Language: Zh Journal: Zhonghua Fu Chan Ke Za Zhi Year: 2008 Type: Article Affiliation country: China

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