A proposed common mechanism by which phorbol esters and epidermal growth factor delay the progression from G2 phase to mitosis of HeLa cells through phospholipid metabolites.

Kaszkin, M; Fürstenberger, G; Richards, J; Seidler, L; Kinzel, V

Kaszkin, M; Fürstenberger, G; Richards, J; Seidler, L; Kinzel, V.

Affiliation

Kaszkin M; Institute of Experimental Pathology, German Cancer Research Center, Heidelberg.

Cancer Res ; 51(16): 4328-35, 1991 Aug 15.

Article in En | MEDLINE | ID: mdl-1868456

Subject(s)

Epidermal Growth Factor/pharmacology; G2 Phase/drug effects; Mitosis/drug effects; Phosphatidic Acids/metabolism; Phospholipids/metabolism; Tetradecanoylphorbol Acetate/pharmacology; Arachidonic Acids/metabolism; Diglycerides/metabolism; HeLa Cells/cytology; HeLa Cells/drug effects; HeLa Cells/metabolism; Humans; Kinetics; Protein Kinase C/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidic Acids / Phospholipids / Tetradecanoylphorbol Acetate / G2 Phase / Epidermal Growth Factor / Mitosis Limits: Humans Language: En Journal: Cancer Res Year: 1991 Type: Article

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