KIT activation in uterine cervix adenosquamous carcinomas by KIT/SCF autocrine/paracrine stimulation loops.

Martinho, Olga; Gonçalves, Alberto; Moreira, Marise A R; Ribeiro, Luiz F J; Queiroz, Geraldo S; Schmitt, Fernando C; Reis, Rui M; Longatto-Filho, Adhemar

Martinho, Olga; Gonçalves, Alberto; Moreira, Marise A R; Ribeiro, Luiz F J; Queiroz, Geraldo S; Schmitt, Fernando C; Reis, Rui M; Longatto-Filho, Adhemar.

Affiliation

Martinho O; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.

Gynecol Oncol ; 111(2): 350-5, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18708242

Subject(s)

Carcinoma, Adenosquamous/enzymology; Proto-Oncogene Proteins c-kit/metabolism; Stem Cell Factor/metabolism; Uterine Cervical Neoplasms/enzymology; Adult; Aged; Carcinoma, Adenosquamous/genetics; Carcinoma, Adenosquamous/pathology; Enzyme Activation; Female; Gene Amplification; Humans; Immunohistochemistry; Middle Aged; Mutation; Phosphorylation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-kit/biosynthesis; Proto-Oncogene Proteins c-kit/genetics; Stem Cell Factor/biosynthesis; Uterine Cervical Neoplasms/genetics; Uterine Cervical Neoplasms/pathology; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Carcinoma, Adenosquamous / Stem Cell Factor / Proto-Oncogene Proteins c-kit Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Gynecol Oncol Year: 2008 Type: Article Affiliation country: Portugal

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