New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin.

Bargieri, Daniel Y; Rosa, Daniela S; Braga, Catarina J M; Carvalho, Bruna O; Costa, Fabio T M; Espíndola, Noeli Maria; Vaz, Adelaide José; Soares, Irene S; Ferreira, Luis C S; Rodrigues, Mauricio M

Bargieri, Daniel Y; Rosa, Daniela S; Braga, Catarina J M; Carvalho, Bruna O; Costa, Fabio T M; Espíndola, Noeli Maria; Vaz, Adelaide José; Soares, Irene S; Ferreira, Luis C S; Rodrigues, Mauricio M.

Affiliation

Bargieri DY; Centro Interdisciplinar de Terapia Gênica (CINTERGEN), Universidade Federal de São Paulo, Escola Paulista de Medicina, Rua Mirassol 207, São Paulo, SP, Brazil.

Vaccine ; 26(48): 6132-42, 2008 Nov 11.

Article in En | MEDLINE | ID: mdl-18804504

Subject(s)

Adjuvants, Immunologic; Flagellin/pharmacology; Malaria Vaccines/immunology; Merozoite Surface Protein 1/immunology; Plasmodium vivax/immunology; Salmonella typhimurium/metabolism; Toll-Like Receptor 5/agonists; Administration, Intranasal; Animals; Antibodies, Monoclonal/biosynthesis; Antibodies, Monoclonal/immunology; Chemistry, Pharmaceutical; Female; Flagellin/isolation & purification; Fluorescent Antibody Technique, Indirect; Immunization Schedule; Injections, Subcutaneous; Malaria Vaccines/administration & dosage; Malaria Vaccines/genetics; Merozoite Surface Protein 1/genetics; Mice; Mice, Inbred C57BL; Plasmodium vivax/genetics; Th1 Cells/immunology; Th2 Cells/immunology; Vaccines, Synthetic/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium vivax / Salmonella typhimurium / Adjuvants, Immunologic / Malaria Vaccines / Merozoite Surface Protein 1 / Toll-Like Receptor 5 / Flagellin Limits: Animals Language: En Journal: Vaccine Year: 2008 Type: Article Affiliation country: Brazil

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