Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice.

Granado, Noelia; O'Shea, Esther; Bove, Jordi; Vila, Miquel; Colado, Ma Isabel; Moratalla, Rosario

Granado, Noelia; O'Shea, Esther; Bove, Jordi; Vila, Miquel; Colado, Ma Isabel; Moratalla, Rosario.

Affiliation

Granado N; Instituto Cajal, Consejo Superior de Investigaciones Científicas, CSIC, Madrid, Spain.

J Neurochem ; 107(4): 1102-12, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18823368

Subject(s)

Corpus Striatum/drug effects; Dopamine/metabolism; N-Methyl-3,4-methylenedioxyamphetamine/administration & dosage; Neurotoxins/administration & dosage; Substantia Nigra/drug effects; Animals; Cell Death/drug effects; Corpus Striatum/cytology; Dopamine Plasma Membrane Transport Proteins/metabolism; Dose-Response Relationship, Drug; Fever/chemically induced; Glial Fibrillary Acidic Protein/metabolism; Macrophage-1 Antigen/metabolism; Male; Mice; Mice, Inbred C57BL; Neurons/drug effects; Neurons/metabolism; Nitric Oxide Synthase/metabolism; Stereotaxic Techniques; Substantia Nigra/cytology; Time Factors; Tyrosine 3-Monooxygenase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Substantia Nigra / Dopamine / N-Methyl-3,4-methylenedioxyamphetamine / Corpus Striatum / Neurotoxins Limits: Animals Language: En Journal: J Neurochem Year: 2008 Type: Article Affiliation country: Spain

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