Interleukin-6 induces the (2'-5') oligoadenylate synthetase gene in M1 cells through an effect on the interferon-responsive enhancer.

Cohen, B; Gothelf, Y; Vaiman, D; Chen, L; Revel, M; Chebath, J

Cohen, B; Gothelf, Y; Vaiman, D; Chen, L; Revel, M; Chebath, J.

Affiliation

Cohen B; Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel.

Cytokine ; 3(2): 83-91, 1991 Mar.

Article in En | MEDLINE | ID: mdl-1888886

Subject(s)

2',5'-Oligoadenylate Synthetase/genetics; Enhancer Elements, Genetic; Interferon Type I/physiology; Interleukin-6/pharmacology; Recombinant Proteins/pharmacology; 2',5'-Oligoadenylate Synthetase/biosynthesis; Animals; Antibodies; Base Sequence; Cell Differentiation/drug effects; Cell Line; DNA, Neoplasm/genetics; DNA, Neoplasm/metabolism; Enzyme Induction; Gene Expression Regulation, Neoplastic/drug effects; Interferon Type I/immunology; Leukemia, Experimental; Mice; Models, Genetic; Molecular Sequence Data; Oligonucleotide Probes; Promoter Regions, Genetic; Protein Binding; Transcriptional Activation; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / 2',5'-Oligoadenylate Synthetase / Interferon Type I / Enhancer Elements, Genetic / Interleukin-6 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cytokine Journal subject: ALERGIA E IMUNOLOGIA Year: 1991 Type: Article Affiliation country: Israel

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