Spectrophotometric determination of clofibrate.

Agrawal, Y K; Patel, D R

Agrawal, Y K; Patel, D R.

Affiliation

Agrawal YK; Pharmacy Department, Faculty of Technology and Engineering, M.S. University of Baroda, Kalabhavan, Baroda 390 001, India.

Talanta ; 34(3): 365-6, 1987 Mar.

Article in En | MEDLINE | ID: mdl-18964315

ABSTRACT

ABSTRACT

A sensitive method for the rapid and accurate determination of clofibrate by hydroxamic acid formation is described. Hydroxylamine hydrochloride is reacted with clofibrate in alkaline medium to give 4-chlorophenoxyisobutyrohydroxamic acid, which forms a purple complex with iron(III) in acidic medium. Common excipients do not interfere.

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Collection: 01-internacional Database: MEDLINE Language: En Journal: Talanta Year: 1987 Type: Article Affiliation country: India

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PubMed Links

Collection: 01-internacional Database: MEDLINE Language: En Journal: Talanta Year: 1987 Type: Article Affiliation country: India