PARP-1 is involved in autophagy induced by DNA damage.

Muñoz-Gámez, José Antonio; Rodríguez-Vargas, José Manuel; Quiles-Pérez, Rosa; Aguilar-Quesada, Rocío; Martín-Oliva, David; de Murcia, Gilbert; Menissier de Murcia, Josiane; Almendros, Antonio; Ruiz de Almodóvar, Mariano; Oliver, F Javier

Muñoz-Gámez, José Antonio; Rodríguez-Vargas, José Manuel; Quiles-Pérez, Rosa; Aguilar-Quesada, Rocío; Martín-Oliva, David; de Murcia, Gilbert; Menissier de Murcia, Josiane; Almendros, Antonio; Ruiz de Almodóvar, Mariano; Oliver, F Javier.

Affiliation

Muñoz-Gámez JA; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd) and Laboratory of Medical Research, Academical Hospital San Cecilio, Granada, Spain.

Autophagy ; 5(1): 61-74, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19001878

Subject(s)

Autophagy; DNA Damage; Poly(ADP-ribose) Polymerases/metabolism; 1-Naphthylamine/analogs & derivatives; 1-Naphthylamine/pharmacology; 3T3 Cells; Adenosine Triphosphate/deficiency; Animals; Apoptosis/drug effects; Apoptosis Regulatory Proteins; Autophagy/drug effects; Autophagy/genetics; Autophagy-Related Protein 5; Beclin-1; Cell Survival/drug effects; Doxorubicin/pharmacology; Enzyme Activation/drug effects; Gene Deletion; Mice; Microtubule-Associated Proteins/metabolism; Mitochondria/drug effects; Mitochondria/enzymology; Mitochondria/ultrastructure; Models, Biological; NAD/deficiency; Naphthalimides/pharmacology; Necrosis/enzymology; Poly(ADP-ribose) Polymerase Inhibitors; Protein Kinases/metabolism; Proteins/metabolism; Quinolones/pharmacology; Subcellular Fractions/drug effects; Subcellular Fractions/metabolism; TOR Serine-Threonine Kinases; Up-Regulation/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / DNA Damage / Poly(ADP-ribose) Polymerases Type of study: Prognostic_studies Language: En Journal: Autophagy Year: 2009 Type: Article Affiliation country: Spain

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