A retrospective analysis of the potential impact of IgG antibodies to agalsidase beta on efficacy during enzyme replacement therapy for Fabry disease.

Bénichou, Bernard; Goyal, Sunita; Sung, Crystal; Norfleet, Andrea M; O'Brien, Fanny

Bénichou, Bernard; Goyal, Sunita; Sung, Crystal; Norfleet, Andrea M; O'Brien, Fanny.

Affiliation

Bénichou B; Genzyme Europe, 33-35 Bd de la Paix, Parc d'activités du Bel-Air, 78105 Saint-Germain-en-Laye Cedex, France. bernard.benichou@genzyme.com

Mol Genet Metab ; 96(1): 4-12, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19022694

Subject(s)

Fabry Disease/drug therapy; Fabry Disease/immunology; Immunoglobulin G/blood; Isoenzymes/therapeutic use; alpha-Galactosidase/therapeutic use; Adult; Fabry Disease/enzymology; Female; Humans; Isoenzymes/immunology; Male; Middle Aged; Retrospective Studies; Skin/metabolism; Treatment Outcome; Trihexosylceramides/blood; Trihexosylceramides/metabolism; alpha-Galactosidase/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Fabry Disease / Alpha-Galactosidase / Isoenzymes Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Mol Genet Metab Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / METABOLISMO Year: 2009 Type: Article Affiliation country: France

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