A novel technology for the production of a heterologous lipoprotein immunogen in high yield has implications for the field of vaccine design.

Chen, Hsin-Wei; Liu, Shih-Jen; Liu, Hsueh-Hung; Kwok, Yan; Lin, Chang-Ling; Lin, Li-Hsiu; Chen, Mei-Yu; Tsai, Jy-Ping; Chang, Li-Sheng; Chiu, Fang-Feng; Lai, Li-wei; Lian, Wei-Cheng; Yang, Chiou-Ying; Hsieh, Shih-Yang; Chong, Pele; Leng, Chih-Hsiang

Chen, Hsin-Wei; Liu, Shih-Jen; Liu, Hsueh-Hung; Kwok, Yan; Lin, Chang-Ling; Lin, Li-Hsiu; Chen, Mei-Yu; Tsai, Jy-Ping; Chang, Li-Sheng; Chiu, Fang-Feng; Lai, Li-wei; Lian, Wei-Cheng; Yang, Chiou-Ying; Hsieh, Shih-Yang; Chong, Pele; Leng, Chih-Hsiang.

Affiliation

Chen HW; Vaccine Research and Development Center, National Health Research Institutes, Zhunan Town, Miaoli 350, Taiwan, ROC.

Vaccine ; 27(9): 1400-9, 2009 Feb 25.

Article in En | MEDLINE | ID: mdl-19150476

Subject(s)

Bacterial Proteins/immunology; Lipoproteins/immunology; Vaccines, Synthetic/immunology; Vaccines/biosynthesis; Amino Acid Sequence; Bacterial Proteins/biosynthesis; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Base Sequence; Cloning, Molecular; DNA Primers; Drug Design; Escherichia coli/genetics; Lipoproteins/biosynthesis; Molecular Sequence Data; Neutralization Tests; Peptide Fragments/biosynthesis; Peptide Fragments/immunology; Recombinant Proteins/biosynthesis; Recombinant Proteins/immunology; Vaccines, Synthetic/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Vaccines / Vaccines, Synthetic / Lipoproteins Language: En Journal: Vaccine Year: 2009 Type: Article

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