[Real-time contrast-enhanced ultrasound in the evaluation of focal liver lesions: diagnostic efficacy and economical issues from a French multicentric study]. / Echographie de contraste temps réel dans la prise en charge diagnostique des lésions nodulaires hépatiques: évaluation des performances diagnostiques et de l'impact économique sur une étude multicentrique française.
J Radiol
; 90(1 Pt 2): 109-22, 2009 Jan.
Article
in Fr
| MEDLINE
| ID: mdl-19212279
ABSTRACT
The recent introduction of high-end ultrasound equipment combined with recent contrast agents provides marked improvements in the characterization of focal liver lesions as previously reported by monocentric studies. The aim of the present study was to evaluate the diagnostic performance of Contrast-Enhanced Ultrasonography (CEUS) using SonoVue as well as its medico-economic value for characterization of focal liver lesions. These nodules were not characterized on previous CT or conventional sonography. This prospective multicentric study conducted in 15 French centres found diagnostic performances similar to those reported for CT and MRI, with a concordance rate of 84.5%, sensitivity greater than 80% and specificity greater than 90% for all types of lesions. Higher acceptance was found for CEUS compared to other imaging modalities. Economical assessment based on examination reimbursment and contrast agent cost showed a lower cost for contrast ultrasound versus CT and MRI. This French multicentric study confirmed the high diagnostic value of CEUS for focal liver lesion characterization and demonstrated a lower economical impact compared to other imaging modalities such as CT and MRI.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phospholipids
/
Sulfur Hexafluoride
/
Ultrasonography
/
Carcinoma, Hepatocellular
/
Contrast Media
/
Focal Nodular Hyperplasia
/
Hemangioma
/
Liver Neoplasms
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Evaluation_studies
/
Health_economic_evaluation
/
Observational_studies
Limits:
Adolescent
/
Adult
/
Humans
Country/Region as subject:
Europa
Language:
Fr
Journal:
J Radiol
Year:
2009
Type:
Article
Affiliation country:
France