The D4Z4 macrosatellite repeat acts as a CTCF and A-type lamins-dependent insulator in facio-scapulo-humeral dystrophy.

Ottaviani, Alexandre; Rival-Gervier, Sylvie; Boussouar, Amina; Foerster, Andrea M; Rondier, Delphine; Sacconi, Sabrina; Desnuelle, Claude; Gilson, Eric; Magdinier, Frédérique

Ottaviani, Alexandre; Rival-Gervier, Sylvie; Boussouar, Amina; Foerster, Andrea M; Rondier, Delphine; Sacconi, Sabrina; Desnuelle, Claude; Gilson, Eric; Magdinier, Frédérique.

Affiliation

Ottaviani A; Laboratoire de Biologie Moléculaire de la Cellule, Ecole Normale Supérieure de Lyon, Centre National de la Recherche Scientifique UMR 5239, UCBL1, IFR128, Lyon, France.

PLoS Genet ; 5(2): e1000394, 2009 Feb.

Article in En | MEDLINE | ID: mdl-19247430

Subject(s)

DNA, Satellite; DNA-Binding Proteins/metabolism; Insulator Elements; Lamin Type A/metabolism; Muscular Dystrophy, Facioscapulohumeral/genetics; Repressor Proteins/metabolism; CCCTC-Binding Factor; Cell Line; Chromosome Mapping; Chromosomes, Human, Pair 4/genetics; DNA-Binding Proteins/genetics; Humans; Lamin Type A/genetics; Muscular Dystrophy, Facioscapulohumeral/metabolism; Protein Binding; Repressor Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / DNA, Satellite / Muscular Dystrophy, Facioscapulohumeral / Lamin Type A / Insulator Elements / DNA-Binding Proteins Limits: Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2009 Type: Article Affiliation country: France

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