Therapeutic potential of proapoptotic molecule Noxa in the selective elimination of tumor cells.

Suzuki, Saori; Nakasato, Makoto; Shibue, Tsukasa; Koshima, Isao; Taniguchi, Tadatsugu

Suzuki, Saori; Nakasato, Makoto; Shibue, Tsukasa; Koshima, Isao; Taniguchi, Tadatsugu.

Affiliation

Suzuki S; Department of Immunology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Cancer Sci ; 100(4): 759-69, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19298224

Subject(s)

Apoptosis/genetics; Breast Neoplasms/pathology; Breast Neoplasms/therapy; Genetic Therapy; Proto-Oncogene Proteins c-bcl-2/physiology; Adenoviridae/genetics; Animals; Breast Neoplasms/genetics; Cell Line, Tumor; Female; Fluorescein-5-isothiocyanate/metabolism; Fluorescent Dyes/metabolism; Glutathione Transferase/metabolism; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Models, Biological; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; Recombinant Proteins/metabolism; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Genetic Therapy / Apoptosis / Proto-Oncogene Proteins c-bcl-2 Limits: Animals / Female / Humans Language: En Journal: Cancer Sci Year: 2009 Type: Article Affiliation country: Japan

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