Polycyclic aromatic hydrocarbons from diesel emissions exert proallergic effects in birch pollen allergic individuals through enhanced mediator release from basophils.

Lubitz, Stefanie; Schober, Wolfgang; Pusch, Gudrun; Effner, Renate; Klopp, Norman; Behrendt, Heidrun; Buters, Jeroen T M

Lubitz, Stefanie; Schober, Wolfgang; Pusch, Gudrun; Effner, Renate; Klopp, Norman; Behrendt, Heidrun; Buters, Jeroen T M.

Affiliation

Lubitz S; Division of Environmental Dermatology and Allergy, Helmholtz Zentrum München/TUM, ZAUM - Center for Allergy and Environment, Technische Universität München, 80802 Munich, Germany.

Environ Toxicol ; 25(2): 188-97, 2010 Apr.

Article in En | MEDLINE | ID: mdl-19382185

Subject(s)

Adjuvants, Immunologic/pharmacology; Air Pollutants/pharmacology; Antigens, Plant/immunology; Basophils/immunology; Polycyclic Aromatic Hydrocarbons/pharmacology; Rhinitis, Allergic, Seasonal/immunology; Vehicle Emissions; Adult; Antigens, CD/metabolism; Basophils/drug effects; Benzo(a)pyrene/pharmacology; Cytokines/metabolism; Female; Histamine/metabolism; Humans; Male; Particulate Matter/pharmacology; Phenanthrenes/pharmacology; Platelet Membrane Glycoproteins/metabolism; Rhinitis, Allergic, Seasonal/genetics; Tetraspanin 30; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycyclic Aromatic Hydrocarbons / Basophils / Vehicle Emissions / Adjuvants, Immunologic / Rhinitis, Allergic, Seasonal / Air Pollutants / Antigens, Plant Type of study: Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Environ Toxicol Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2010 Type: Article Affiliation country: Germany

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