Ex vivo expanded human CD4+CD25+Foxp3+ regulatory T cells prevent lethal xenogenic graft versus host disease (GVHD).

Cao, Tinghua; Soto, Allis; Zhou, Wei; Wang, Weihong; Eck, Steven; Walker, Mindi; Harriman, Gregory; Li, Li

Cao, Tinghua; Soto, Allis; Zhou, Wei; Wang, Weihong; Eck, Steven; Walker, Mindi; Harriman, Gregory; Li, Li.

Affiliation

Cao T; Therakos Inc., Exton, PA 19341, USA. tinghuacao@hotmail.com

Cell Immunol ; 258(1): 65-71, 2009.

Article in En | MEDLINE | ID: mdl-19410243

Subject(s)

Graft vs Host Disease/immunology; Graft vs Host Disease/prevention & control; T-Lymphocytes, Regulatory/immunology; T-Lymphocytes, Regulatory/transplantation; Transplantation, Heterologous/immunology; Animals; Antigens, CD/immunology; Antigens, CD/metabolism; CTLA-4 Antigen; Cell Culture Techniques; Forkhead Transcription Factors/immunology; Forkhead Transcription Factors/metabolism; Graft vs Host Disease/metabolism; Graft vs Host Disease/mortality; Humans; Interleukin-2 Receptor alpha Subunit/immunology; Interleukin-2 Receptor alpha Subunit/metabolism; L-Selectin/immunology; L-Selectin/metabolism; Mice; Mice, SCID; T-Lymphocytes, Regulatory/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Heterologous / T-Lymphocytes, Regulatory / Graft vs Host Disease Limits: Animals / Humans Language: En Journal: Cell Immunol Year: 2009 Type: Article Affiliation country: United States

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