Alcohol abuse and de novo tumors in liver transplantation.
Transplant Proc
; 41(4): 1310-2, 2009 May.
Article
in En
| MEDLINE
| ID: mdl-19460548
ABSTRACT
INTRODUCTION:
Organ transplant recipients show an increased incidence of cancer ranging from 4% to 16% owing to several causes immunosuppression, viral infection, individual predisposition, and so on. MATERIALS ANDMETHODS:
We retrospectively reviewed the records of 43/683 (6.3%) recipients of 734 liver transplants performed from November 1991 to November 2008 who experienced a de novo neoplasm.CONCLUSION:
Alcohol abuse significantly increased the rate of all de novo neoplasms and particularly pharyngogastroesophageal cancers among population of liver transplant recipients. Minimization of immunosuppressive therapy is necessary to reduce the risk of a de novo neoplasm. Strict posttransplant follow-up is required to identify early gastroenteric tumors.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Liver Transplantation
/
Alcoholism
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Transplant Proc
Year:
2009
Type:
Article
Affiliation country:
Italy