Recent advances in synthesis of PAR ligands as therapeutic strategy for inflammatory diseases.
Mini Rev Med Chem
; 9(6): 653-63, 2009 Jun.
Article
in En
| MEDLINE
| ID: mdl-19519491
ABSTRACT
Several studies have been published on discovering involvement of PARs receptors in a number of disease states, including cancer and inflammation of the cardiovascular, respiratory, musculoskeletal, gastrointestinal and nervous systems. This mini-review will focus on recent advances in the synthesis of PAR ligands highlighting their therapeutic potential in the treatment of various inflammatory diseases.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Organic Chemicals
/
Receptors, Proteinase-Activated
/
Inflammation
Limits:
Animals
/
Humans
Language:
En
Journal:
Mini Rev Med Chem
Journal subject:
QUIMICA
Year:
2009
Type:
Article
Affiliation country:
Italy