CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta.

Bollyky, Paul L; Falk, Ben A; Long, S Alice; Preisinger, Anton; Braun, Kathy R; Wu, Rebecca P; Evanko, Stephen P; Buckner, Jane H; Wight, Thomas N; Nepom, Gerald T

Bollyky, Paul L; Falk, Ben A; Long, S Alice; Preisinger, Anton; Braun, Kathy R; Wu, Rebecca P; Evanko, Stephen P; Buckner, Jane H; Wight, Thomas N; Nepom, Gerald T.

Affiliation

Bollyky PL; Benaroya Research Institute, Seattle, WA 98101, USA. pbollyky@benaroyaresearch.org

J Immunol ; 183(4): 2232-41, 2009 Aug 15.

Article in En | MEDLINE | ID: mdl-19635906

Subject(s)

Forkhead Transcription Factors/biosynthesis; Hyaluronan Receptors/physiology; Interleukin-10/biosynthesis; Interleukin-2/biosynthesis; T-Lymphocyte Subsets/cytology; T-Lymphocyte Subsets/immunology; T-Lymphocytes, Regulatory/immunology; Transforming Growth Factor beta/biosynthesis; Animals; Cell Survival/genetics; Cell Survival/immunology; Cells, Cultured; Forkhead Transcription Factors/genetics; Gene Knock-In Techniques; Humans; Hyaluronan Receptors/genetics; Hyaluronan Receptors/metabolism; Hyaluronic Acid/metabolism; Hyaluronic Acid/physiology; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction/genetics; T-Lymphocyte Subsets/metabolism; T-Lymphocytes, Regulatory/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocyte Subsets / Transforming Growth Factor beta / Interleukin-2 / Interleukin-10 / T-Lymphocytes, Regulatory / Hyaluronan Receptors / Forkhead Transcription Factors Limits: Animals / Humans Language: En Journal: J Immunol Year: 2009 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google