Structure-activity relationships in 1,4-benzodioxan-related compounds. 2. Role of the amine function on alpha-adrenoreceptor blocking activity.

Giardinà, D; Gulini, U; Pigini, M; Piloni, M G; Melchiorre, C

Giardinà, D; Gulini, U; Pigini, M; Piloni, M G; Melchiorre, C.

Affiliation

Giardinà D; Dipartimento di Scienze Chimiche, Università di Camerino.

Farmaco ; 45(12): 1289-98, 1990 Dec.

Article in En | MEDLINE | ID: mdl-1982488

Subject(s)

Adrenergic alpha-Antagonists/chemical synthesis; Dioxanes/chemical synthesis; Adrenergic alpha-Antagonists/pharmacology; Animals; Clonidine/antagonists & inhibitors; Clonidine/pharmacology; Cocaine/pharmacology; Dioxanes/pharmacology; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction/drug effects; Muscle, Smooth/drug effects; Norepinephrine/antagonists & inhibitors; Propranolol/pharmacology; Rats; Structure-Activity Relationship; Vas Deferens/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Adrenergic alpha-Antagonists / Dioxanes Limits: Animals Language: En Journal: Farmaco Journal subject: FARMACOLOGIA / QUIMICA Year: 1990 Type: Article

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