Investigation of soy sauce treated with nitrite in the chromosomal aberration test in vitro and the micronucleus test in vivo.
Mutat Res
; 262(3): 171-6, 1991 Mar.
Article
in En
| MEDLINE
| ID: mdl-2002815
ABSTRACT
Soy sauce pretreated with 2300 ppm nitrite caused no more aberrations than did untreated soy sauce in the chromosomal aberration test in vitro using a Chinese hamster fibroblast cell line with or without S9 mixture. The aberration induction by soy sauce is likely to be caused by the 17% sodium chloride it contains. Soy sauce with or without pretreatment with 2300 ppm nitrite was orally given to ICR mice at a dose of 14 ml/kg body weight once or 6 ml/kg body weight/day for 5 consecutive days. This oral administration did not induce any significant increase in micronuclei in the micronucleus test in vivo.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Glycine max
/
Micronucleus Tests
/
Chromosome Aberrations
/
Condiments
/
Nitrites
Limits:
Animals
Language:
En
Journal:
Mutat Res
Year:
1991
Type:
Article
Affiliation country:
Japan