Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide.

Glaser, Nicole; Yuen, Natalie; Anderson, Steven E; Tancredi, Daniel J; O'Donnell, Martha E

Glaser, Nicole; Yuen, Natalie; Anderson, Steven E; Tancredi, Daniel J; O'Donnell, Martha E.

Affiliation

Glaser N; Department of Pediatrics, University of California, Davis, California, USA. nsglaser@ucdavis.edu

Diabetes ; 59(3): 702-9, 2010 Mar.

Article in En | MEDLINE | ID: mdl-20028943

Subject(s)

Brain Edema/drug therapy; Bumetanide/pharmacology; Diabetic Ketoacidosis/drug therapy; Fluid Therapy; Insulin/pharmacology; Animals; Aspartic Acid/analogs & derivatives; Aspartic Acid/metabolism; Brain/blood supply; Brain/metabolism; Brain Edema/etiology; Brain Edema/metabolism; Cerebrovascular Circulation/drug effects; Cerebrovascular Circulation/physiology; Creatinine/metabolism; Diabetic Ketoacidosis/complications; Diabetic Ketoacidosis/metabolism; Diuretics/pharmacology; Hypoglycemic Agents/pharmacology; Infusions, Intravenous; Lactic Acid/metabolism; Magnetic Resonance Spectroscopy; Phosphocreatine/metabolism; Rats; Rats, Sprague-Dawley; Sodium Chloride/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Edema / Bumetanide / Diabetic Ketoacidosis / Fluid Therapy / Insulin Type of study: Etiology_studies Limits: Animals Language: En Journal: Diabetes Year: 2010 Type: Article Affiliation country: United States

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