Influence of serogroup B meningococcal vaccine antigens on growth and survival of the meningococcus in vitro and in ex vivo and in vivo models of infection.

Seib, Kate L; Oriente, Francesca; Adu-Bobie, Jeannette; Montanari, Paolo; Ferlicca, Francesca; Giuliani, Marzia M; Rappuoli, Rino; Pizza, Mariagrazia; Delany, Isabel

Seib, Kate L; Oriente, Francesca; Adu-Bobie, Jeannette; Montanari, Paolo; Ferlicca, Francesca; Giuliani, Marzia M; Rappuoli, Rino; Pizza, Mariagrazia; Delany, Isabel.

Affiliation

Seib KL; Novartis Vaccines, Via Fiorentina 1, 53100 Siena, Italy. kate.seib@novartis.com <kate.seib@novartis.com>

Vaccine ; 28(12): 2416-27, 2010 Mar 11.

Article in En | MEDLINE | ID: mdl-20067752

Subject(s)

Antigens, Bacterial/physiology; Microbial Viability; Neisseria meningitidis, Serogroup B/pathogenicity; Animals; Antigens, Bacterial/genetics; Biomass; Blood Bactericidal Activity; Clinical Trials as Topic; Colony Count, Microbial; Gene Deletion; Humans; Meningococcal Vaccines/immunology; Mutagenesis, Insertional; Neisseria meningitidis, Serogroup B/genetics; Nephelometry and Turbidimetry; Rats; Rats, Wistar; Stress, Physiological; Virulence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neisseria meningitidis, Serogroup B / Microbial Viability / Antigens, Bacterial Limits: Animals / Humans Language: En Journal: Vaccine Year: 2010 Type: Article

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