A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation.

Sobieszczuk, Dorothy F; Poliakov, Alexei; Xu, Qiling; Wilkinson, David G

Sobieszczuk, Dorothy F; Poliakov, Alexei; Xu, Qiling; Wilkinson, David G.

Affiliation

Sobieszczuk DF; Division of Developmental Neurobiology, MRC National Institute for Medical Research, London NW7 1AA, United Kingdom.

Genes Dev ; 24(2): 206-18, 2010 Jan 15.

Article in En | MEDLINE | ID: mdl-20080956

Subject(s)

Carrier Proteins/metabolism; Cell Differentiation; Feedback, Physiological/physiology; Neurogenesis/physiology; Neurons/cytology; Zebrafish Proteins/metabolism; Animals; Carrier Proteins/genetics; Cell Line; Chick Embryo; Chickens; Conserved Sequence; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Humans; Kruppel-Like Transcription Factors/antagonists & inhibitors; Kruppel-Like Transcription Factors/metabolism; Nerve Tissue Proteins/genetics; Neurons/physiology; Protein Transport; Ubiquitination; Zebrafish/embryology; Zebrafish Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carrier Proteins / Cell Differentiation / Zebrafish Proteins / Feedback, Physiological / Neurogenesis / Neurons Limits: Animals / Humans Language: En Journal: Genes Dev Journal subject: BIOLOGIA MOLECULAR Year: 2010 Type: Article Affiliation country: United kingdom

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