Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression.

Meier, Ingo D; Bernreuther, Christian; Tilling, Thomas; Neidhardt, John; Wong, Yong Wee; Schulze, Christian; Streichert, Thomas; Schachner, Melitta

Meier, Ingo D; Bernreuther, Christian; Tilling, Thomas; Neidhardt, John; Wong, Yong Wee; Schulze, Christian; Streichert, Thomas; Schachner, Melitta.

Affiliation

Meier ID; Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

FASEB J ; 24(6): 1714-24, 2010 Jun.

Article in En | MEDLINE | ID: mdl-20110269

Subject(s)

Base Sequence/genetics; Biomarkers/metabolism; CD56 Antigen/physiology; Gene Expression; Gene Targeting; Tenascin/physiology; Animals; Blotting, Northern; Blotting, Western; Gene Expression Profiling; Genetic Vectors; Integrases/metabolism; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Small Nucleolar/metabolism; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Base Sequence / Biomarkers / Gene Expression / Gene Targeting / Tenascin / CD56 Antigen Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2010 Type: Article Affiliation country: Germany

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