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Prompt and successful toxin-targeting treatment of three patients with necrotizing pneumonia due to Staphylococcus aureus strains carrying the Panton-Valentine leukocidin genes.
Rouzic, Nicolas; Janvier, Frédéric; Libert, Nicolas; Javouhey, Etienne; Lina, Gerard; Nizou, Jacques-Yves; Pasquier, Pierre; Stamm, Didier; Brinquin, Louis; Pelletier, Christophe; Vandenesch, François; Floret, Daniel; Etienne, Jerome; Gillet, Yves.
Affiliation
  • Rouzic N; Université de Lyon, INSERM U851, Faculté de Médecine Lyon Est, 7 Rue Guillaume Paradin, 69372 Lyon Cedex 08, France.
J Clin Microbiol ; 48(5): 1952-5, 2010 May.
Article in En | MEDLINE | ID: mdl-20129956
ABSTRACT
Three patients with extensive necrotizing pneumonia due to Panton-Valentine leukocidin-positive Staphylococcus aureus strains and with aggravating factors (leukopenia count of less than 3x10(9)/liter in all three cases and hemoptysis in two cases) were successfully treated with toxin-suppressing agents introduced rapidly after hospital admission.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Staphylococcal / Staphylococcus aureus / Bacterial Toxins / Antitoxins / Immunoglobulins, Intravenous / Virulence Factors / Exotoxins / Leukocidins / Necrosis Limits: Adult / Humans / Infant / Male Language: En Journal: J Clin Microbiol Year: 2010 Type: Article Affiliation country: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Staphylococcal / Staphylococcus aureus / Bacterial Toxins / Antitoxins / Immunoglobulins, Intravenous / Virulence Factors / Exotoxins / Leukocidins / Necrosis Limits: Adult / Humans / Infant / Male Language: En Journal: J Clin Microbiol Year: 2010 Type: Article Affiliation country: France