Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases.

Urscher, Miriam; Przyborski, Jude M; Imoto, Masaya; Deponte, Marcel

Urscher, Miriam; Przyborski, Jude M; Imoto, Masaya; Deponte, Marcel.

Affiliation

Urscher M; Butenandt Institute for Physiological Chemistry, Ludwig-Maximilians University, Munich, Germany.

Mol Microbiol ; 76(1): 92-103, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20149108

Subject(s)

Cytosol/chemistry; Dimerization; Lactoylglutathione Lyase/metabolism; Organelles/chemistry; Plasmodium falciparum/enzymology; Protozoan Proteins/metabolism; Thiolester Hydrolases/metabolism; Biphenyl Compounds/pharmacology; Chromatography, Gel; Curcumin/pharmacology; Enzyme Inhibitors/pharmacology; Ethers/pharmacology; Inhibitory Concentration 50; Lactoylglutathione Lyase/antagonists & inhibitors; Lactoylglutathione Lyase/chemistry; Lactoylglutathione Lyase/isolation & purification; Molecular Structure; Molecular Weight; Plasmodium falciparum/chemistry; Protozoan Proteins/antagonists & inhibitors; Protozoan Proteins/chemistry; Protozoan Proteins/isolation & purification; Thiolester Hydrolases/antagonists & inhibitors; Thiolester Hydrolases/chemistry; Thiolester Hydrolases/isolation & purification

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Thiolester Hydrolases / Organelles / Protozoan Proteins / Dimerization / Cytosol / Lactoylglutathione Lyase Language: En Journal: Mol Microbiol Journal subject: BIOLOGIA MOLECULAR / MICROBIOLOGIA Year: 2010 Type: Article Affiliation country: Germany

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