The lack of an inherent membrane targeting signal is responsible for the failure of the matrix (M1) protein of influenza A virus to bud into virus-like particles.

Wang, Dan; Harmon, Aaron; Jin, Jing; Francis, David H; Christopher-Hennings, Jane; Nelson, Eric; Montelaro, Ronald C; Li, Feng

Wang, Dan; Harmon, Aaron; Jin, Jing; Francis, David H; Christopher-Hennings, Jane; Nelson, Eric; Montelaro, Ronald C; Li, Feng.

Affiliation

Wang D; Department of Biology and Microbiology, South Dakota State University, Brookings, SD 57007, USA.

J Virol ; 84(9): 4673-81, 2010 May.

Article in En | MEDLINE | ID: mdl-20181696

Subject(s)

Cell Membrane/virology; Influenza A Virus, H1N1 Subtype/physiology; Protein Sorting Signals; Viral Matrix Proteins/genetics; Virus Release; Animals; Cell Line; Cell Membrane/chemistry; Cell Nucleus/chemistry; Cell Nucleus/virology; Chlorocebus aethiops; Dogs; Humans; Viral Matrix Proteins/metabolism; Virosomes/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Sorting Signals / Cell Membrane / Viral Matrix Proteins / Influenza A Virus, H1N1 Subtype / Virus Release Limits: Animals / Humans Language: En Journal: J Virol Year: 2010 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google