Central deficiency of corticotropin-releasing hormone receptor type 1 (CRH-R1) abolishes effects of CRH on NREM but not on REM sleep in mice.

Romanowski, Christoph P N; Fenzl, Thomas; Flachskamm, Cornelia; Wurst, Wolfgang; Holsboer, Florian; Deussing, Jan M; Kimura, Mayumi

Romanowski, Christoph P N; Fenzl, Thomas; Flachskamm, Cornelia; Wurst, Wolfgang; Holsboer, Florian; Deussing, Jan M; Kimura, Mayumi.

Affiliation

Romanowski CP; Max Planck Institute of Psychiatry, Munich, Germany.

Sleep ; 33(4): 427-36, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20394311

Subject(s)

Corticotropin-Releasing Hormone/administration & dosage; Receptors, Corticotropin-Releasing Hormone/deficiency; Sleep, REM/drug effects; Animals; Arousal/drug effects; Corticosterone/blood; Corticotropin-Releasing Hormone/blood; Dose-Response Relationship, Drug; Electroencephalography/methods; Electromyography/methods; Hypothalamo-Hypophyseal System/drug effects; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pituitary-Adrenal System/drug effects; Receptors, Corticotropin-Releasing Hormone/blood; Sleep Stages/drug effects; Time Factors; Wakefulness/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sleep, REM / Corticotropin-Releasing Hormone / Receptors, Corticotropin-Releasing Hormone Limits: Animals Language: En Journal: Sleep Year: 2010 Type: Article Affiliation country: Germany

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