Immunoglobulin heavy chain variable region genes contribute to the induction of thyroid-stimulating antibodies in recombinant inbred mice.

Rapoport, B; Williams, R W; Chen, C-R; McLachlan, S M

Rapoport, B; Williams, R W; Chen, C-R; McLachlan, S M.

Affiliation

Rapoport B; Cedars-Sinai Research Institute and UCLA School of Medicine, Los Angeles, CA 90048, USA.

Genes Immun ; 11(3): 254-63, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20407472

Subject(s)

Genes, Immunoglobulin Heavy Chain/genetics; Immunoglobulin Variable Region/genetics; Immunoglobulins, Thyroid-Stimulating/immunology; Animals; CHO Cells; Chromosome Mapping; Cricetinae; Cricetulus; Genome-Wide Association Study; Graves Disease/genetics; Graves Disease/immunology; Humans; Hyperthyroidism/genetics; Hyperthyroidism/immunology; Immunization/methods; Immunoglobulins, Thyroid-Stimulating/blood; Immunoglobulins, Thyroid-Stimulating/genetics; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Receptors, Thyrotropin/genetics; Receptors, Thyrotropin/immunology; Recombination, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Variable Region / Immunoglobulins, Thyroid-Stimulating / Genes, Immunoglobulin Heavy Chain Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Genes Immun Journal subject: ALERGIA E IMUNOLOGIA / BIOLOGIA MOLECULAR Year: 2010 Type: Article Affiliation country: United States

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