Effect of steady-state enoxacin on single-dose pharmacokinetics of roflumilast and roflumilast N-oxide.

Lahu, Gezim; Nassr, Nassr; Herzog, Rolf; Elmlinger, Martin; Ruth, Peter; Hinder, Markus; Huennemeyer, Andreas

Lahu, Gezim; Nassr, Nassr; Herzog, Rolf; Elmlinger, Martin; Ruth, Peter; Hinder, Markus; Huennemeyer, Andreas.

Affiliation

Lahu G; Nycomed GmbH, Konstanz, Germany. gezim.lahu@nycomed.com

J Clin Pharmacol ; 51(4): 586-93, 2011 Apr.

Article in En | MEDLINE | ID: mdl-20466871

Subject(s)

Aminopyridines/administration & dosage; Aminopyridines/pharmacokinetics; Benzamides/administration & dosage; Benzamides/pharmacokinetics; Enoxacin/administration & dosage; Enoxacin/pharmacokinetics; Administration, Oral; Adult; Aminopyridines/adverse effects; Benzamides/adverse effects; Cyclopropanes/administration & dosage; Cyclopropanes/adverse effects; Cyclopropanes/pharmacokinetics; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A/metabolism; Drug Interactions; Enoxacin/adverse effects; Female; Humans; Male; Phosphodiesterase 4 Inhibitors/administration & dosage; Phosphodiesterase 4 Inhibitors/adverse effects; Phosphodiesterase 4 Inhibitors/pharmacokinetics; Young Adult

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzamides / Enoxacin / Aminopyridines Limits: Adult / Female / Humans / Male Language: En Journal: J Clin Pharmacol Year: 2011 Type: Article Affiliation country: Germany

Fulltext

XML

PubMed Links

Search on Google