A genetic determinant of the striatal dopamine response to alcohol in men.

Ramchandani, V A; Umhau, J; Pavon, F J; Ruiz-Velasco, V; Margas, W; Sun, H; Damadzic, R; Eskay, R; Schoor, M; Thorsell, A; Schwandt, M L; Sommer, W H; George, D T; Parsons, L H; Herscovitch, P; Hommer, D; Heilig, M

Ramchandani, V A; Umhau, J; Pavon, F J; Ruiz-Velasco, V; Margas, W; Sun, H; Damadzic, R; Eskay, R; Schoor, M; Thorsell, A; Schwandt, M L; Sommer, W H; George, D T; Parsons, L H; Herscovitch, P; Hommer, D; Heilig, M.

Affiliation

Ramchandani VA; Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.

Mol Psychiatry ; 16(8): 809-17, 2011 Aug.

Article in En | MEDLINE | ID: mdl-20479755

Subject(s)

Alcoholism/genetics; Corpus Striatum/metabolism; Dopamine/metabolism; Ethanol/pharmacology; Genetic Predisposition to Disease/genetics; Receptors, Opioid, mu/genetics; Receptors, Opioid, mu/physiology; Adult; Alleles; Animals; Corpus Striatum/physiology; Dopamine/physiology; Genetic Variation; Genotype; Heterozygote; Humans; Male; Mice; Mice, Transgenic; Middle Aged; Positron-Emission Tomography/methods; Raclopride

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dopamine / Receptors, Opioid, mu / Corpus Striatum / Genetic Predisposition to Disease / Ethanol / Alcoholism Type of study: Clinical_trials Limits: Adult / Animals / Humans / Male / Middle aged Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2011 Type: Article Affiliation country: United States

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