Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4.

Antonios, Diane; Rousseau, Philippe; Larangé, Alexandre; Kerdine-Römer, Saadia; Pallardy, Marc

Antonios, Diane; Rousseau, Philippe; Larangé, Alexandre; Kerdine-Römer, Saadia; Pallardy, Marc.

Affiliation

Antonios D; Universud, Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche S 749 and 996, Faculté de Pharmacie, Châtenay-Malabry, France.

J Immunol ; 185(1): 89-98, 2010 Jul 01.

Article in En | MEDLINE | ID: mdl-20525893

Subject(s)

Dendritic Cells/immunology; Dendritic Cells/metabolism; Interleukin-1/biosynthesis; Irritants/toxicity; Nickel/toxicity; Cells, Cultured; Dendritic Cells/enzymology; Humans; Interferon Regulatory Factor-1/antagonists & inhibitors; Interferon Regulatory Factor-1/metabolism; Interferon Regulatory Factor-1/physiology; Interferon-gamma/physiology; Interleukin-12/biosynthesis; Interleukin-12/metabolism; Interleukin-12 Subunit p35/biosynthesis; Interleukin-12 Subunit p35/genetics; Interleukin-12 Subunit p40/biosynthesis; JNK Mitogen-Activated Protein Kinases/physiology; MAP Kinase Signaling System/immunology; Monocytes/enzymology; Monocytes/immunology; Monocytes/metabolism; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; NF-kappa B/physiology; RNA, Messenger/biosynthesis; STAT1 Transcription Factor/physiology; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors; p38 Mitogen-Activated Protein Kinases/metabolism; p38 Mitogen-Activated Protein Kinases/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Interleukin-1 / Irritants / Nickel Limits: Humans Language: En Journal: J Immunol Year: 2010 Type: Article Affiliation country: France

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