CXCL12 gene expression is upregulated by hypoxia and growth arrest but not by inflammatory cytokines in rheumatoid synovial fibroblasts.

Santiago, Begoña; Calonge, Esther; Del Rey, Manuel J; Gutierrez-Cañas, Irene; Izquierdo, Elena; Usategui, Alicia; Galindo, María; Alcamí, José; Pablos, José L

Santiago, Begoña; Calonge, Esther; Del Rey, Manuel J; Gutierrez-Cañas, Irene; Izquierdo, Elena; Usategui, Alicia; Galindo, María; Alcamí, José; Pablos, José L.

Affiliation

Santiago B; Servicio de Reumatología y Unidad de Investigación, Hospital 12 de Octubre, Madrid, Spain.

Cytokine ; 53(2): 184-90, 2011 Feb.

Article in En | MEDLINE | ID: mdl-20609598

Subject(s)

Arthritis, Rheumatoid/pathology; Chemokine CXCL12/genetics; Fibroblasts/drug effects; Fibroblasts/metabolism; Inflammation Mediators/pharmacology; Synovial Fluid/cytology; Up-Regulation/genetics; Base Sequence; Cell Hypoxia/drug effects; Cell Proliferation/drug effects; Chemokine CXCL12/metabolism; Consensus Sequence/genetics; Humans; Intercellular Signaling Peptides and Proteins/pharmacology; Promoter Regions, Genetic/genetics; Protein Binding/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism; Synovial Fluid/drug effects; Transcription Factors/metabolism; Transcription, Genetic/drug effects; Up-Regulation/drug effects; Vascular Endothelial Growth Factor A/genetics; Vascular Endothelial Growth Factor A/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Synovial Fluid / Up-Regulation / Inflammation Mediators / Chemokine CXCL12 / Fibroblasts Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cytokine Journal subject: ALERGIA E IMUNOLOGIA Year: 2011 Type: Article Affiliation country: Spain

Fulltext

XML

PubMed Links

Search on Google