Mice with inactivation of aryl hydrocarbon receptor-interacting protein (Aip) display complete penetrance of pituitary adenomas with aberrant ARNT expression.

Raitila, Anniina; Lehtonen, Heli J; Arola, Johanna; Heliövaara, Elina; Ahlsten, Manuel; Georgitsi, Marianthi; Jalanko, Anu; Paetau, Anders; Aaltonen, Lauri A; Karhu, Auli

Raitila, Anniina; Lehtonen, Heli J; Arola, Johanna; Heliövaara, Elina; Ahlsten, Manuel; Georgitsi, Marianthi; Jalanko, Anu; Paetau, Anders; Aaltonen, Lauri A; Karhu, Auli.

Affiliation

Raitila A; Department of Medical Genetics, University of Helsinki, Helsinki, Finland.

Am J Pathol ; 177(4): 1969-76, 2010 Oct.

Article in En | MEDLINE | ID: mdl-20709796

Subject(s)

Aryl Hydrocarbon Receptor Nuclear Translocator/metabolism; Growth Hormone-Secreting Pituitary Adenoma/etiology; Growth Hormone-Secreting Pituitary Adenoma/pathology; Intracellular Signaling Peptides and Proteins/physiology; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator/genetics; Blotting, Western; Cell Proliferation; Female; Growth Hormone-Secreting Pituitary Adenoma/metabolism; Humans; Immunoenzyme Techniques; Loss of Heterozygosity; Male; Mice; Mice, Inbred C57BL; RNA, Messenger/genetics; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intracellular Signaling Peptides and Proteins / Growth Hormone-Secreting Pituitary Adenoma / Aryl Hydrocarbon Receptor Nuclear Translocator Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Am J Pathol Year: 2010 Type: Article Affiliation country: Finland

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