Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease.

Aouba, Achille; Georgin-Lavialle, Sophie; Pagnoux, Christian; Martin Silva, Nicolas; Renand, Amédée; Galateau-Salle, Françoise; Le Toquin, Sophie; Bensadoun, Henri; Larousserie, Frederique; Silvera, Stéphane; Provost, Nicole; Candon, Sophie; Seror, Raphaèle; de Menthon, Mathilde; Hermine, Olivier; Guillevin, Loïc; Bienvenu, Boris

Aouba, Achille; Georgin-Lavialle, Sophie; Pagnoux, Christian; Martin Silva, Nicolas; Renand, Amédée; Galateau-Salle, Françoise; Le Toquin, Sophie; Bensadoun, Henri; Larousserie, Frederique; Silvera, Stéphane; Provost, Nicole; Candon, Sophie; Seror, Raphaèle; de Menthon, Mathilde; Hermine, Olivier; Guillevin, Loïc; Bienvenu, Boris.

Affiliation

Aouba A; Department of Internal Medicine, French National Referral Center for Langerhans Cell Histiocytosis, Hôpital Cochin, Université de Paris Descartes, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France. achille.aouba@nck.aphp.fr

Blood ; 116(20): 4070-6, 2010 Nov 18.

Article in En | MEDLINE | ID: mdl-20724540

Subject(s)

Erdheim-Chester Disease/metabolism; Interleukin-1alpha/metabolism; Adult; C-Reactive Protein/metabolism; Drug Tolerance; Erdheim-Chester Disease/diagnostic imaging; Erdheim-Chester Disease/drug therapy; Female; Humans; Interleukin 1 Receptor Antagonist Protein/pharmacology; Interleukin 1 Receptor Antagonist Protein/therapeutic use; Male; Middle Aged; Monocytes/drug effects; Monocytes/metabolism; Radiography; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erdheim-Chester Disease / Interleukin-1alpha Type of study: Diagnostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Blood Year: 2010 Type: Article Affiliation country: France

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