Loss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation.

Lussier, Carine R; Brial, François; Roy, Sébastien A B; Langlois, Marie-Josée; Verdu, Elena F; Rivard, Nathalie; Perreault, Nathalie; Boudreau, François

Lussier, Carine R; Brial, François; Roy, Sébastien A B; Langlois, Marie-Josée; Verdu, Elena F; Rivard, Nathalie; Perreault, Nathalie; Boudreau, François.

Affiliation

Lussier CR; Département d'Anatomie et Biologie Cellulaire, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

PLoS One ; 5(8): e12378, 2010 Aug 24.

Article in En | MEDLINE | ID: mdl-20808783

Subject(s)

Cell Differentiation; Hepatocyte Nuclear Factor 1-alpha/deficiency; Hepatocyte Nuclear Factor 1-alpha/genetics; Intestinal Mucosa/cytology; Intestinal Mucosa/metabolism; Animals; Biological Transport/genetics; Cell Proliferation; Enterocytes/cytology; Enterocytes/metabolism; Enteroendocrine Cells/cytology; Enteroendocrine Cells/metabolism; Gene Deletion; Gene Knockout Techniques; Glucose/metabolism; Hepatocyte Nuclear Factor 1-alpha/metabolism; Homeostasis/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Mice; Paneth Cells/cytology; Paneth Cells/metabolism; Protein Serine-Threonine Kinases/metabolism; Signal Transduction/genetics; TOR Serine-Threonine Kinases; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Hepatocyte Nuclear Factor 1-alpha / Intestinal Mucosa Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2010 Type: Article Affiliation country: Canada

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